Type 1 Diabetes Mellitus
What is Type 1 Diabetes Mellitus? Type 1 Diabetes Mellitus is a form of diabetes that occurs due to autoimmune destruction of the insulin producing pancreatic beta cells. The loss of insulin producing...
View ArticleAddison’s Disease
What is Addison’s disease? Addison’s disease involves the underproduction of cortisol & aldosterone by the adrenal cortex The disease is very rare with around 8 in a million people developing the...
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How the Adrenal Axis Works
What is the Adrenal Axis? The adrenal axis (hypothalamic-pituitary-adrenal axis) refers to a complex set of interactions and feedback loops between the hypothalamus, pituitary and adrenal glands. This...
View ArticleCushing’s Syndrome
What is Cushing’s Syndrome? Cushing’s Syndrome refers to a disease process caused by abnormally high levels of Cortisol This can result from overdose of glucocorticoid drugs or from tumours producing...
View ArticleType 2 Diabetes Mellitus
What is Type 2 Diabetes Mellitus? Type 2 Diabetes Mellitus is a disorder of metabolism characterised by high levels of glucose in the blood as a result of insulin resistance and insulin deficiency....
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How the Gonadal Axis Works
What is the gonadal axis? The gonadal axis comprises of the interaction between the hypothalamus, pituitary gland and the gonads. The system works together to regulate development, reproduction,...
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The Menstrual Cycle
What is the menstrual cycle? The menstrual cycle is a complex series of physiological changes occurring in women on a monthly basis. It results in production of an ovum & thickening of the...
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Diabetes Insipidus
What is Diabetes Insipidus? Diabetes Insipidus is a disease characterised by the passage of large volumes (>3L/24hrs) of dilute urine (osmolality <300 mOsmol/Kg)¹. It affects approximately 3 in...
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Syndrome of inappropriate antidiuretic hormone secretion
What is SIADH? The syndrome of inappropriate antidiuretic hormone secretion (SIADH) involves the excessive secretion of antidiuretic hormone (ADH) from the posterior pituitary gland or another source....
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Hyperparathyroidism
What is Hyperparathyroidism? Hyperparathyroidism is characterised by excessive production of parathyroid hormone (PTH) by the parathyroid glands. There are 4 of these glands in the neck, located behind...
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Hyperthyroidism
What is Hyperthyroidism? Hyperthyroidism is a disease process caused by the presence of an overactive thyroid gland which in turn results in excessive production of thyroid hormones (T3 & T4) When...
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Hypothyroidism
What is Hypothyroidism? Hypothyroidism refers to the presence of an under-active thyroid gland which causes a deficiency of thyroid hormones (T3 & T4). When hypothyroidism becomes symptomatic it...
View ArticleAcromegaly
What is Acromegaly? Acromegaly is a disease caused by the overproduction of growth hormone (GH) after an individual has reached adulthood and epiphyseal plate (growth plate) closure has occurred. This...
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How the adrenal axis works
What is the adrenal axis? The adrenal axis (hypothalamic-pituitary-adrenal axis) refers to a complex set of interactions and feedback loops between the hypothalamus, pituitary and adrenal glands. This...
View ArticleClik here to view.
How the gonadal axis works
What is the gonadal axis? The gonadal axis involves a complex interaction between the hypothalamus, pituitary gland and the gonads. The system works together to regulate development, reproduction,...
View ArticleClik here to view.
The Menstrual Cycle
What is the menstrual cycle? The menstrual cycle is a complex series of physiological changes occurring in women on a monthly basis. It results in production of an ovum and thickening of the...
View ArticleClik here to view.
Diabetes insipidus
What is diabetes insipidus? Diabetes insipidus is a disease characterised by the passage of large volumes (>3L/24hrs) of dilute urine (osmolality <300 mOsmol/Kg)¹. It affects approximately 3 in...
View ArticleClik here to view.
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
What is SIADH? The syndrome of inappropriate antidiuretic hormone secretion (SIADH) involves the excessive secretion of antidiuretic hormone (ADH) from the posterior pituitary gland or another source....
View ArticleClik here to view.
How the adrenal axis works
What is the adrenal axis? The adrenal axis (hypothalamic-pituitary-adrenal axis) refers to a complex set of interactions and feedback loops between the hypothalamus, pituitary and adrenal glands. This...
View ArticleClik here to view.
How the gonadal axis works
What is the gonadal axis? The gonadal axis involves a complex interaction between the hypothalamus, pituitary gland and the gonads. The system works together to regulate development, reproduction,...
View Article